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The right preclinical models with the best translational
and predictive services at ONE PLACE.
JC Discovery® developed a comprehensive range of advanced tools and knowledge to establish your genetically modified in vivo and in vitro models and then access cutting-edge translational services to characterize them.
They include high content immunoprofiling to support pharma and biotech strategic drug development in the field of oncology, immuno-oncology, inflammation, auto-immunity, and infectiology.
The in vitro (T-cell, human cell lines, PDX-derived cells) and in vivo (CDX, PDX, mice and rats immunodeficient, syngenic and humanized models) developed by JC Discovery® benefit from the latest advances in genome editing (CRISPR-Cas9) in compliance with the 3R rules (reduce, refine, replace), ethics, and animal welfare.
The in vitro (T-cell, human cell lines, PDX-derived cells) and in vivo (CDX, PDX, mice and rats immunodeficient, syngenic and humanized models) developed by JC Discovery™ benefit from the latest advances in genome editing (CRISPR-Cas9) in compliance with the 3R rules (reduce, refine, replace), ethics and animal welfare.
Understanding the mechanism of action of immuno-modulatory therapies is a key step of your development projects.
At JC Discovery®, we developed expertise and integrated toolbox to allow deep immunoprofiling (in normal and pathological conditions) using validated mice, rats and humanized mouse models that are best adapted to your drug development.
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Understanding the mechanism of action of immuno-modulatory therapies is a key step of your development projects.
At JC DiscoveryTM, we developed expertise and integrated toolbox to allow deep immunoprofiling using mice, rats and refined preclinical humanized mice models that are best adapted to your drug development.
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Advanced omics to perform target validation, optimization, and elucidate mode of action before stepping into clinical steps.
Secure and breed the newly created models of interest in optimal conditions to initiate your preclinical trials quickly and safely.
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The Fast-Track™ Delivery Solution is an integrated logistics service that ensures the packaging and transport of animals.
What are JC Discovery® services?
JC Discovery® develops highly predictive in vitro and in vivo models of human diseases to increase the clinical translatability. It helps leading biopharmaceutical companies and academic research institutions to validate and develop novel therapeutic candidates acting on immune system in the field of immuno-oncology, inflammation, auto-immune, and infectious diseases. At JC Discovery®, we provide encompassing genetic engineering models and preclinical services to make drug discovery phase a strategic time frame to decide the future of your drug, at the early phase of development.
What are the advantages to work with JC Discovery®?
Long-lasting expertise, state-of-the-art infrastructure, and robust data mining, JC Discovery® gives access to key stage services enabling drug target validation, compound validation and clinical trial optimization. Understanding core pathways within immune system to comprehensively study disease mechanisms are also translational preclinical services that we are offering.
Why does JC Discovery® offer these high value services?
Drug discovery and development is a long, complex, costly, and high-risk process that takes over 10–15 years with an average cost of over $1–2 billion for each new drug to be approved for clinical use. Advance a therapeutic candidate to phase I clinical trial is very challenging. JC Discovery® has developped the Fast-TrackTM solutions to help you take the decision at the discovery stage and give your drug candidate the best chance to enter and succeed in the preclinical and clinical phases.
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